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Solvent-Free Synthesis, DNA-Topoisomerase II Activity and Molecular Docking Study of New Asymmetrically N,N'-Substituted Ureas

A new series of asymmetrically N,N'-substituted ureas 20–25 was prepared using solvent free conditions, which is an eco-friendly methodology, starting with Schiff bases derived from cinnamaldehyde and p-substituted anilines, which are subsequently submitted to reduction reactions that afford th...

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Detalles Bibliográficos
Autores principales:	Esteves-Souza, Andressa, Rodrigues-Santos, Claudio E., Cistia, Catarina de Nigris Del, da Silva, Daniel Rosa, Sant’Anna, Carlos Maurício R., Echevarria, Aurea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269040/ https://www.ncbi.nlm.nih.gov/pubmed/23117429 http://dx.doi.org/10.3390/molecules171112882

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