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Acylated mono-, bis- and tris- Cinchona-Based Amines Containing Ferrocene or Organic Residues: Synthesis, Structure and in Vitro Antitumor Activity on Selected Human Cancer Cell Lines

A series of novel functionalized mono-, bis- and tris-(S)-{[(2S,4R,8R)-8-ethyl-quinuclidin-2-yl](6-methoxyquinolin-4-yl)}methanamines including ferrocene-containing derivatives was obtained by the reaction of the precursor amine with a variety of acylation agents. Their in vitro antitumor activity w...

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Detalles Bibliográficos
Autores principales: Károlyi, Benedek Imre, Bősze, Szilvia, Orbán, Erika, Sohár, Pál, Drahos, László, Gál, Emese, Csámpai, Antal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269053/
https://www.ncbi.nlm.nih.gov/pubmed/22367026
http://dx.doi.org/10.3390/molecules17032316