Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes

A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni...

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Autores principales: Gwaram, Nura Suleiman, Ali, Hapipah Mohd, Khaledi, Hamid, Abdulla, Mahmood Ameen, Hadi, A. Hamid A., Lin, Thong Kwai, Ching, Chai Lay, Ooi, Cher Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269056/
https://www.ncbi.nlm.nih.gov/pubmed/22609786
http://dx.doi.org/10.3390/molecules17055952
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author Gwaram, Nura Suleiman
Ali, Hapipah Mohd
Khaledi, Hamid
Abdulla, Mahmood Ameen
Hadi, A. Hamid A.
Lin, Thong Kwai
Ching, Chai Lay
Ooi, Cher Lin
author_facet Gwaram, Nura Suleiman
Ali, Hapipah Mohd
Khaledi, Hamid
Abdulla, Mahmood Ameen
Hadi, A. Hamid A.
Lin, Thong Kwai
Ching, Chai Lay
Ooi, Cher Lin
author_sort Gwaram, Nura Suleiman
collection PubMed
description A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa.
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spelling pubmed-62690562018-12-20 Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes Gwaram, Nura Suleiman Ali, Hapipah Mohd Khaledi, Hamid Abdulla, Mahmood Ameen Hadi, A. Hamid A. Lin, Thong Kwai Ching, Chai Lay Ooi, Cher Lin Molecules Article A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa. MDPI 2012-05-18 /pmc/articles/PMC6269056/ /pubmed/22609786 http://dx.doi.org/10.3390/molecules17055952 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Gwaram, Nura Suleiman
Ali, Hapipah Mohd
Khaledi, Hamid
Abdulla, Mahmood Ameen
Hadi, A. Hamid A.
Lin, Thong Kwai
Ching, Chai Lay
Ooi, Cher Lin
Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_full Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_fullStr Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_full_unstemmed Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_short Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_sort antibacterial evaluation of some schiff bases derived from 2-acetylpyridine and their metal complexes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269056/
https://www.ncbi.nlm.nih.gov/pubmed/22609786
http://dx.doi.org/10.3390/molecules17055952
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