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Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk
Multiple sclerosis is a complex neurological disease, with ∼20% of risk heritability attributable to common genetic variants, including >230 identified by genome-wide association studies. Multiple strands of evidence suggest that much of the remaining heritability is also due to additive effects...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
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Cell Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269166/ https://www.ncbi.nlm.nih.gov/pubmed/30343897 http://dx.doi.org/10.1016/j.cell.2018.09.049 |
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