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Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways

Although trisomy 12 (+12) chronic lymphocytic leukemia (CLL) comprises about 20% of cases, relatively little is known about its pathophysiology. These cases often demonstrate atypical morphological and immunophenotypic features, high proliferative rates, unmutated immunoglobulin heavy chain variable...

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Detalles Bibliográficos
Autores principales:	Abruzzo, Lynne V., Herling, Carmen D., Calin, George A., Oakes, Christopher, Barron, Lynn L., Banks, Haley E., Katju, Vikram, Keating, Michael J., Coombes, Kevin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269288/ https://www.ncbi.nlm.nih.gov/pubmed/29976738 http://dx.doi.org/10.3324/haematol.2018.190132

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