Niche TWIST1 is critical for maintaining normal hematopoiesis and impeding leukemia progression

The bone marrow microenvironment regulates normal and malignant hematopoiesis, but the underlying molecular mechanisms remain poorly defined. Using a chimeric mice model, we demonstrate that Twist1 deletion in the bone marrow microenvironment results in alteration of multiple niche cells as well as...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyan, Ma, Yanping, Li, Rongrong, Guo, Dan, Wang, Nan, Zhao, Yangyang, Yin, Jing, Ren, Qian, Lin, Yongmin, Ma, Xiaotong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269292/
https://www.ncbi.nlm.nih.gov/pubmed/30026340
http://dx.doi.org/10.3324/haematol.2018.190652

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