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Rhaponticum carthamoides transformed root extract inhibits human glioma cells viability, induces double strand DNA damage, H2A.X phosphorylation, and PARP1 cleavage

Rhaponticum carthamoides transformed root extract induces double strand DNA damage by increasing the number of phosphorylated H2A.X- and cleaved PARP1-positive U87MG cells and patient-derived IV grade glioma cells. Furthermore, treatment of these cells with root extract causes down-regulation of UHR...

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Detalles Bibliográficos
Autores principales:	Skała, Ewa, Toma, Monika, Kowalczyk, Tomasz, Śliwiński, Tomasz, Sitarek, Przemysław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269353/ https://www.ncbi.nlm.nih.gov/pubmed/30171426 http://dx.doi.org/10.1007/s10616-018-0251-3

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