Adipocyte OGT governs diet-induced hyperphagia and obesity

Palatable foods (fat and sweet) induce hyperphagia, and facilitate the development of obesity. Whether and how overnutrition increases appetite through the adipose-to-brain axis is unclear. O-linked beta-D-N-acetylglucosamine (O-GlcNAc) transferase (OGT) couples nutrient cues to O-GlcNAcylation of i...

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Detalles Bibliográficos
Autores principales: Li, Min-Dian, Vera, Nicholas B., Yang, Yunfan, Zhang, Bichen, Ni, Weiming, Ziso-Qejvanaj, Enida, Ding, Sheng, Zhang, Kaisi, Yin, Ruonan, Wang, Simeng, Zhou, Xu, Fang, Ethan X., Xu, Tian, Erion, Derek M., Yang, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269424/
https://www.ncbi.nlm.nih.gov/pubmed/30504766
http://dx.doi.org/10.1038/s41467-018-07461-x

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