Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6(+) cancer cell and macrophage polarization

It remains controversial whether targeting tumour vasculature can improve radiotherapeutic efficacy. We report that radiation-induced endothelial-to-mesenchymal transition (EndMT) leads to tumour vasculature with abnormal SMA(+)NG2(+) pericyte recruitment during tumour regrowth after radiotherapy. T...

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Detalles Bibliográficos
Autores principales: Choi, Seo-Hyun, Kim, A-Ram, Nam, Jae-Kyung, Kim, Jin-Mo, Kim, Jee-Youn, Seo, Haeng Ran, Lee, Hae-June, Cho, Jaeho, Lee, Yoon-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269447/
https://www.ncbi.nlm.nih.gov/pubmed/30504836
http://dx.doi.org/10.1038/s41467-018-07470-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269447/
https://www.ncbi.nlm.nih.gov/pubmed/30504836
http://dx.doi.org/10.1038/s41467-018-07470-w

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