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Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
The increasing number of severe infections with multi-drug-resistant pathogens worldwide highlights the need for alternative treatment options. Given the pivotal role of phagocytes and especially alveolar macrophages in pulmonary immunity, we introduce a new, cell-based treatment strategy to target...
Autores principales: | Ackermann, Mania, Kempf, Henning, Hetzel, Miriam, Hesse, Christina, Hashtchin, Anna Rafiei, Brinkert, Kerstin, Schott, Juliane Wilhelmine, Haake, Kathrin, Kühnel, Mark Philipp, Glage, Silke, Figueiredo, Constanca, Jonigk, Danny, Sewald, Katherina, Schambach, Axel, Wronski, Sabine, Moritz, Thomas, Martin, Ulrich, Zweigerdt, Robert, Munder, Antje, Lachmann, Nico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269475/ https://www.ncbi.nlm.nih.gov/pubmed/30504915 http://dx.doi.org/10.1038/s41467-018-07570-7 |
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