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High density Huh7.5 cell hollow fiber bioreactor culture for high-yield production of hepatitis C virus and studies of antivirals
Chronic hepatitis C virus (HCV) infection poses a serious global public health burden. Despite the recent development of effective treatments there is a large unmet need for a prophylactic vaccine. Further, antiviral resistance might compromise treatment efficiency in the future. HCV cell culture sy...
Autores principales: | Pihl, Anne F., Offersgaard, Anna F., Mathiesen, Christian K., Prentoe, Jannick, Fahnøe, Ulrik, Krarup, Henrik, Bukh, Jens, Gottwein, Judith M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269495/ https://www.ncbi.nlm.nih.gov/pubmed/30504788 http://dx.doi.org/10.1038/s41598-018-35010-5 |
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