Mapping of a responsible region for sex reversal upstream of Sox9 by production of mice with serial deletion in a genomic locus

Sox9 plays critical roles in testis formation. By mapping four familial cases of disorders of sexual development, a 32.5 kb sequence located far upstream of SOX9 was previously identified as being a commonly deleted region and named the XY sex reversal region (XYSR). To narrow down a responsible seq...

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Detalles Bibliográficos
Autores principales: Ogawa, Yuya, Terao, Miho, Hara, Satoshi, Tamano, Moe, Okayasu, Haruka, Kato, Tomoko, Takada, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269501/
https://www.ncbi.nlm.nih.gov/pubmed/30504911
http://dx.doi.org/10.1038/s41598-018-35746-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269501/
https://www.ncbi.nlm.nih.gov/pubmed/30504911
http://dx.doi.org/10.1038/s41598-018-35746-0

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