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Mathematical modelling of a hypoxia-regulated oncolytic virus delivered by tumour-associated macrophages
Tumour hypoxia has long presented a challenge for cancer therapy: Poor vascularisation in hypoxic regions hinders both the delivery of chemotherapeutic agents and the response to radiotherapy, and hypoxic cancer cells that survive treatment can trigger tumour regrowth after treatment has ended. Tumo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269600/ https://www.ncbi.nlm.nih.gov/pubmed/30359572 http://dx.doi.org/10.1016/j.jtbi.2018.10.044 |