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Identification and Physicochemical Characteristics of Temozolomide Process-Related Impurities

In this article the crystal structures of the starting material TZ-5 and the key intermediate TZ-6 of temozolomide (TZ-7), an anticancer therapeutic agent, are presented, together with their spectroscopic and thermal characteristics. Both compounds crystallize in the triclinic P-1 space group. X-ray...

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Detalles Bibliográficos
Autores principales: Łaszcz, Marta, Kubiszewski, Marek, Jedynak, Łukasz, Kaczmarska, Monika, Kaczmarek, Łukasz, Łuniewski, Wojciech, Gabarski, Krzysztof, Witkowska, Anna, Kuziak, Krzysztof, Malińska, Maura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269663/
https://www.ncbi.nlm.nih.gov/pubmed/24335615
http://dx.doi.org/10.3390/molecules181215344