Cargando…

Structural Characterization by NMR of a Double Phosphorylated Chimeric Peptide Vaccine for Treatment of Alzheimer’s Disease

Rational design of peptide vaccines becomes important for the treatment of some diseases such as Alzheimer’s disease (AD) and related disorders. In this study, as part of a larger effort to explore correlations of structure and activity, we attempt to characterize the doubly phosphorylated chimeric...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramírez-Gualito, Karla, Richter, Monique, Matzapetakis, Manolis, Singer, David, Berger, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269680/ https://www.ncbi.nlm.nih.gov/pubmed/23624647 http://dx.doi.org/10.3390/molecules18054929

Ejemplares similares

Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer’s Disease Like Tau Aggregation
por: Richter, Monique, et al.
Publicado: (2014)

Exploring the Role of Solvent on Carbohydrate–Aryl Interactions by Diffusion NMR-Based Studies
por: Jütten, Linda, et al.
Publicado: (2018)

The hepatic and skeletal muscle ovine metabolomes as affected by weight loss: a study in three sheep breeds using NMR-metabolomics
por: Palma, Mariana, et al.
Publicado: (2016)

Vaccination with M2e-Based Multiple Antigenic Peptides: Characterization of the B Cell Response and Protection Efficacy in Inbred and Outbred Mice
por: Wolf, Amaya I., et al.
Publicado: (2011)

Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer
por: Mistretta, Brandon, et al.
Publicado: (2023)

Two Residues in the Basic Region of the Yeast Transcription Factor Yap8 Are Crucial for Its DNA-Binding Specificity
por: Amaral, Catarina, et al.
Publicado: (2013)

In-Cell NMR Study of Tau and MARK2 Phosphorylated Tau
por: Zhang, Shengnan, et al.
Publicado: (2018)

C- and N-Phosphorylated Enamines—An Avenue to Heterocycles: NMR Spectroscopy
por: Larina, Lyudmila
Publicado: (2023)

Chimeric Avidin – NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein
por: Tossavainen, Helena, et al.
Publicado: (2014)

How solvent determines the molecular reactive conformation and the selectivity: Solvation spheres and energy
por: Hernández-Lima, Joseelyne, et al.
Publicado: (2022)

Computational Model of Chimeric Antigen Receptors Explains Site-Specific Phosphorylation Kinetics
por: Rohrs, Jennifer A., et al.
Publicado: (2018)

Skeletal muscle metabolomics and blood biochemistry analysis reveal metabolic changes associated with dietary amino acid supplementation in dairy calves
por: Yu, Kuai, et al.
Publicado: (2018)

Chimeric Translation for Mitochondrial Peptides: Regular and Expanded Codons
por: Seligmann, Hervé, et al.
Publicado: (2019)

ASCVac-1, a Multi-Peptide Chimeric Vaccine, Protects Mice Against Ascaris suum Infection
por: Gazzinelli-Guimarães, Ana Clara, et al.
Publicado: (2021)

Unambiguous Tracking of Protein Phosphorylation by Fast High‐Resolution FOSY NMR
por: Lesovoy, Dmitry M., et al.
Publicado: (2021)

Chimeric mitochondrial peptides from contiguous regular and swinger RNA
por: Seligmann, Hervé
Publicado: (2016)

Phosphorylation of amyloid beta (Aβ) peptides – A trigger for formation of toxic aggregates in Alzheimer's disease
por: Kumar, Sathish, et al.
Publicado: (2011)

Mechanical Dilution of Beta-amyloid Peptide and Phosphorylated Tau Protein in Alzheimer's Disease: Too Simple to be True?
por: Menéndez González, Manuel
Publicado: (2017)

Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer’s-like mouse models
por: Kumar, Sathish, et al.
Publicado: (2020)

Fully Automated Characterization of Protein–Peptide Binding by Microfluidic 2D NMR
por: Plata, Marek, et al.
Publicado: (2023)

Data on the peptide mapping and MS identification for phosphorylated peptide
por: Wang, Hui, et al.
Publicado: (2016)

NMR and computational data of two novel antimicrobial peptides
por: Falcigno, Lucia, et al.
Publicado: (2016)

NMR studies of excluded volume interactions in peptide dendrimers
por: Sheveleva, Nadezhda N., et al.
Publicado: (2018)

In-cell Solid-State NMR Studies of Antimicrobial Peptides
por: Separovic, Frances, et al.
Publicado: (2020)

NMR refinement and peptide folding using the GROMACS software
por: Sinelnikova, Anna, et al.
Publicado: (2021)

Current peptide vaccine and immunotherapy approaches against Alzheimer's disease
por: Parrocha, Chelsea Marie T., et al.
Publicado: (2022)

Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort
por: Conde, R., et al.
Publicado: (2022)

Binding Mode Characterization of Osteopontin on Hydroxyapatite by Solution NMR Spectroscopy
por: Holzinger, Julian, et al.
Publicado: (2021)

AC-NP: A Novel Chimeric Peptide with Natriuretic and Vasorelaxing Actions
por: Chen, Bao-Ying, et al.
Publicado: (2011)

A general insert label for peptide display on chimeric filamentous bacteriophages
por: Kaplan, Gilad, et al.
Publicado: (2012)

Comparison of the structure and function of a chimeric peptide modified titanium surface
por: Gong, Lei, et al.
Publicado: (2019)

Solid-State NMR Characterization of Autofluorescent Fibrils Formed by the Elastin-Derived Peptide GVGVAGVG
por: Sharpe, Simon, et al.
Publicado: (2011)

Phosphorylation-induced conformation of β(2)-adrenoceptor related to arrestin recruitment revealed by NMR
por: Shiraishi, Yutaro, et al.
Publicado: (2018)

In-Cell NMR: Analysis of Protein–Small Molecule Interactions, Metabolic Processes, and Protein Phosphorylation
por: Kumar, Amit, et al.
Publicado: (2019)

Peptide Stapling Improves the Sustainability of a Peptide-Based Chimeric Molecule That Induces Targeted Protein Degradation
por: Yokoo, Hidetomo, et al.
Publicado: (2021)

Engineering of Live Chimeric Vaccines against Human Metapneumovirus
por: Ogonczyk Makowska, Daniela, et al.
Publicado: (2020)

Chimeric Vaccines Based on Novel Insect-Specific Flaviviruses
por: Harrison, Jessica J., et al.
Publicado: (2021)

Antimicrobial Peptide Mechanisms Studied by Whole-Cell Deuterium NMR
por: Kumari, Sarika, et al.
Publicado: (2022)

Serum metabolomic profiling unveils distinct sex-related metabolic patterns in NAFLD
por: Fotakis, Charalambos, et al.
Publicado: (2023)

Epigenetic Modulation on Tau Phosphorylation in Alzheimer's Disease
por: Yu, Chao-Chao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lnk6ei08iduj7rqsk33l4g6cp5