Synthesis and SAR Studies of Praziquantel Derivatives with Activity against Schistosoma japonicum

The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as leads for further optimization.

Detalles Bibliográficos
Autores principales: Wang, Wen-Long, Song, Li-Jun, Chen, Xia, Yin, Xu-Ren, Fan, Wen-Hua, Wang, Gu-Ping, Yu, Chuan-Xin, Feng, Bainian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269691/
https://www.ncbi.nlm.nih.gov/pubmed/23912271
http://dx.doi.org/10.3390/molecules18089163

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