Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels

Ten 1,4-disubstituted 1,2,3-triazoles were synthesized from one of 1-(azido-methyl)benzene, 1-(azidomethyl)-4-fluorobenzene, 1-(azidomethyl)-4-chlorobenzene, 1-(azidomethyl)-4-bromobenzene or 1-(azidomethyl)-4-iodobenzene, generated in situ from sodium azide and the corresponding benzyl halide, and...

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Autores principales: Negrón-Silva, Guillermo E., González-Olvera, Rodrigo, Angeles-Beltrán, Deyanira, Maldonado-Carmona, Nidia, Espinoza-Vázquez, Araceli, Palomar-Pardavé, Manuel E., Romero-Romo, Mario A., Santillan, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269733/
https://www.ncbi.nlm.nih.gov/pubmed/23599018
http://dx.doi.org/10.3390/molecules18044613
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author Negrón-Silva, Guillermo E.
González-Olvera, Rodrigo
Angeles-Beltrán, Deyanira
Maldonado-Carmona, Nidia
Espinoza-Vázquez, Araceli
Palomar-Pardavé, Manuel E.
Romero-Romo, Mario A.
Santillan, Rosa
author_facet Negrón-Silva, Guillermo E.
González-Olvera, Rodrigo
Angeles-Beltrán, Deyanira
Maldonado-Carmona, Nidia
Espinoza-Vázquez, Araceli
Palomar-Pardavé, Manuel E.
Romero-Romo, Mario A.
Santillan, Rosa
author_sort Negrón-Silva, Guillermo E.
collection PubMed
description Ten 1,4-disubstituted 1,2,3-triazoles were synthesized from one of 1-(azido-methyl)benzene, 1-(azidomethyl)-4-fluorobenzene, 1-(azidomethyl)-4-chlorobenzene, 1-(azidomethyl)-4-bromobenzene or 1-(azidomethyl)-4-iodobenzene, generated in situ from sodium azide and the corresponding benzyl halide, and dipropargyl uracil or dipropargyl thymine. Optimal experimental conditions were established for the conventional click chemistry. The corrosion inhibiting properties of some of these compounds, which were determined by means of an electrochemical technique, are also presented.
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spelling pubmed-62697332018-12-14 Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels Negrón-Silva, Guillermo E. González-Olvera, Rodrigo Angeles-Beltrán, Deyanira Maldonado-Carmona, Nidia Espinoza-Vázquez, Araceli Palomar-Pardavé, Manuel E. Romero-Romo, Mario A. Santillan, Rosa Molecules Article Ten 1,4-disubstituted 1,2,3-triazoles were synthesized from one of 1-(azido-methyl)benzene, 1-(azidomethyl)-4-fluorobenzene, 1-(azidomethyl)-4-chlorobenzene, 1-(azidomethyl)-4-bromobenzene or 1-(azidomethyl)-4-iodobenzene, generated in situ from sodium azide and the corresponding benzyl halide, and dipropargyl uracil or dipropargyl thymine. Optimal experimental conditions were established for the conventional click chemistry. The corrosion inhibiting properties of some of these compounds, which were determined by means of an electrochemical technique, are also presented. MDPI 2013-04-18 /pmc/articles/PMC6269733/ /pubmed/23599018 http://dx.doi.org/10.3390/molecules18044613 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Negrón-Silva, Guillermo E.
González-Olvera, Rodrigo
Angeles-Beltrán, Deyanira
Maldonado-Carmona, Nidia
Espinoza-Vázquez, Araceli
Palomar-Pardavé, Manuel E.
Romero-Romo, Mario A.
Santillan, Rosa
Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels
title Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels
title_full Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels
title_fullStr Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels
title_full_unstemmed Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels
title_short Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels
title_sort synthesis of new 1,2,3-triazole derivatives of uracil and thymine with potential inhibitory activity against acidic corrosion of steels
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269733/
https://www.ncbi.nlm.nih.gov/pubmed/23599018
http://dx.doi.org/10.3390/molecules18044613
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