Identification of Electronic and Structural Descriptors of Adenosine Analogues Related to Inhibition of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase

Quantitative structure–activity relationship (QSAR) studies were performed in order to identify molecular features responsible for the antileishmanial activity of 61 adenosine analogues acting as inhibitors of the enzyme glyceraldehyde 3-phosphate dehydrogenase of Leishmania mexicana (LmGAPDH). Dens...

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Detalles Bibliográficos
Autores principales: Lozano, Norka B. H., Oliveira, Rafael F., Weber, Karen C., Honorio, Kathia M., Guido, Rafael V., Andricopulo, Adriano D., Da Silva, Albérico B. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269754/
https://www.ncbi.nlm.nih.gov/pubmed/23629757
http://dx.doi.org/10.3390/molecules18055032

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