Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis

Twelve phenolics, including the three new compounds balanophonin C (1), balanophonin D (2), balanophonin E (3), were isolated from the seeds of Lithocarpus pachylepis. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 1–9 were evaluated for t...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Yong, Ma, Guoxu, Wei, Hua, Yuan, Jingquan, Wu, Haifeng, Zhou, Xiaolei, Yang, Junshan, Xu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269783/
https://www.ncbi.nlm.nih.gov/pubmed/23989685
http://dx.doi.org/10.3390/molecules180910397
Descripción
Sumario:Twelve phenolics, including the three new compounds balanophonin C (1), balanophonin D (2), balanophonin E (3), were isolated from the seeds of Lithocarpus pachylepis. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 1–9 were evaluated for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 and showed moderate inhibitory activities, with IC(50) values ranging from 10.9 to 34.7 μM.

Ejemplares similares