Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis

Twelve phenolics, including the three new compounds balanophonin C (1), balanophonin D (2), balanophonin E (3), were isolated from the seeds of Lithocarpus pachylepis. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 1–9 were evaluated for t...

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Detalles Bibliográficos
Autores principales: Xie, Yong, Ma, Guoxu, Wei, Hua, Yuan, Jingquan, Wu, Haifeng, Zhou, Xiaolei, Yang, Junshan, Xu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269783/
https://www.ncbi.nlm.nih.gov/pubmed/23989685
http://dx.doi.org/10.3390/molecules180910397
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author Xie, Yong
Ma, Guoxu
Wei, Hua
Yuan, Jingquan
Wu, Haifeng
Zhou, Xiaolei
Yang, Junshan
Xu, Xudong
author_facet Xie, Yong
Ma, Guoxu
Wei, Hua
Yuan, Jingquan
Wu, Haifeng
Zhou, Xiaolei
Yang, Junshan
Xu, Xudong
author_sort Xie, Yong
collection PubMed
description Twelve phenolics, including the three new compounds balanophonin C (1), balanophonin D (2), balanophonin E (3), were isolated from the seeds of Lithocarpus pachylepis. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 1–9 were evaluated for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 and showed moderate inhibitory activities, with IC(50) values ranging from 10.9 to 34.7 μM.
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spelling pubmed-62697832018-12-18 Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis Xie, Yong Ma, Guoxu Wei, Hua Yuan, Jingquan Wu, Haifeng Zhou, Xiaolei Yang, Junshan Xu, Xudong Molecules Article Twelve phenolics, including the three new compounds balanophonin C (1), balanophonin D (2), balanophonin E (3), were isolated from the seeds of Lithocarpus pachylepis. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 1–9 were evaluated for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 and showed moderate inhibitory activities, with IC(50) values ranging from 10.9 to 34.7 μM. MDPI 2013-08-28 /pmc/articles/PMC6269783/ /pubmed/23989685 http://dx.doi.org/10.3390/molecules180910397 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Xie, Yong
Ma, Guoxu
Wei, Hua
Yuan, Jingquan
Wu, Haifeng
Zhou, Xiaolei
Yang, Junshan
Xu, Xudong
Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis
title Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis
title_full Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis
title_fullStr Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis
title_full_unstemmed Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis
title_short Three New Phenolics and Other Constituents from the Seeds of Lithocarpus pachylepis
title_sort three new phenolics and other constituents from the seeds of lithocarpus pachylepis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269783/
https://www.ncbi.nlm.nih.gov/pubmed/23989685
http://dx.doi.org/10.3390/molecules180910397
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