Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid

An improved synthesis of multifunctionalized pyrrolo[2,3,4-kl]acridine derivatives with different substituted patterns using silica sulfuric acid (SSA) as a heterogeneous catalyst under microwave irradiation conditions was developed. The reaction could be conducted by using readily available and ine...

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Autores principales: Cao, Chengpao, Xu, Changliang, Lin, Wei, Li, Xuemei, Hu, Minghua, Wang, Juxian, Huang, Zhibin, Shi, Daqing, Wang, Yucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269803/
https://www.ncbi.nlm.nih.gov/pubmed/23358320
http://dx.doi.org/10.3390/molecules18021613
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author Cao, Chengpao
Xu, Changliang
Lin, Wei
Li, Xuemei
Hu, Minghua
Wang, Juxian
Huang, Zhibin
Shi, Daqing
Wang, Yucheng
author_facet Cao, Chengpao
Xu, Changliang
Lin, Wei
Li, Xuemei
Hu, Minghua
Wang, Juxian
Huang, Zhibin
Shi, Daqing
Wang, Yucheng
author_sort Cao, Chengpao
collection PubMed
description An improved synthesis of multifunctionalized pyrrolo[2,3,4-kl]acridine derivatives with different substituted patterns using silica sulfuric acid (SSA) as a heterogeneous catalyst under microwave irradiation conditions was developed. The reaction could be conducted by using readily available and inexpensive substrates within short periods of 12–15 min. under microwave irradiation. Compared with the conventional methods, the remarkable advantages of this method are milder reaction conditions, operational simplicity, higher yields, short reaction times, and an environmentally friendly procedure.
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spelling pubmed-62698032018-12-14 Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid Cao, Chengpao Xu, Changliang Lin, Wei Li, Xuemei Hu, Minghua Wang, Juxian Huang, Zhibin Shi, Daqing Wang, Yucheng Molecules Article An improved synthesis of multifunctionalized pyrrolo[2,3,4-kl]acridine derivatives with different substituted patterns using silica sulfuric acid (SSA) as a heterogeneous catalyst under microwave irradiation conditions was developed. The reaction could be conducted by using readily available and inexpensive substrates within short periods of 12–15 min. under microwave irradiation. Compared with the conventional methods, the remarkable advantages of this method are milder reaction conditions, operational simplicity, higher yields, short reaction times, and an environmentally friendly procedure. MDPI 2013-01-28 /pmc/articles/PMC6269803/ /pubmed/23358320 http://dx.doi.org/10.3390/molecules18021613 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Cao, Chengpao
Xu, Changliang
Lin, Wei
Li, Xuemei
Hu, Minghua
Wang, Juxian
Huang, Zhibin
Shi, Daqing
Wang, Yucheng
Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid
title Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid
title_full Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid
title_fullStr Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid
title_full_unstemmed Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid
title_short Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid
title_sort microwave-assisted improved synthesis of pyrrolo[2,3,4-kl]acridine and dihydropyrrolo[2,3,4-kl]acridine derivatives catalyzed by silica sulfuric acid
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269803/
https://www.ncbi.nlm.nih.gov/pubmed/23358320
http://dx.doi.org/10.3390/molecules18021613
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