Sesquiterpene Lactones and Their Derivatives Inhibit High Glucose-Induced NF-κB Activation and MCP-1 and TGF-β1 Expression in Rat Mesangial Cells

Diabetic nephropathy (DN) is one of the most common and serious chronic complications of diabetes mellitus, however, no efficient clinical drugs exist for the treatment of DN. We selected and synthesized several sesquiterpene lactones (SLs), and then used the MTT assay to detect rat mesangial cells...

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Detalles Bibliográficos
Autores principales: Jia, Qian-Qian, Wang, Jian-Cheng, Long, Jing, Zhao, Yan, Chen, Si-Jia, Zhai, Jia-Dai, Wei, Lian-Bo, Zhang, Quan, Chen, Yue, Long, Hai-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269856/
https://www.ncbi.nlm.nih.gov/pubmed/24152676
http://dx.doi.org/10.3390/molecules181013061

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