Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues

Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC(50) =...

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Detalles Bibliográficos
Autores principales: Akhtar, Muhammad Nadeem, Zareen, Seema, Yeap, Swee Keong, Ho, Wan Yong, Lo, Kong Mun, Hasan, Aurangzeb, Alitheen, Noorjahan Banu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269871/
https://www.ncbi.nlm.nih.gov/pubmed/23966087
http://dx.doi.org/10.3390/molecules180810042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269871/
https://www.ncbi.nlm.nih.gov/pubmed/23966087
http://dx.doi.org/10.3390/molecules180810042

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