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Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues
Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC(50) =...
Autores principales: | Akhtar, Muhammad Nadeem, Zareen, Seema, Yeap, Swee Keong, Ho, Wan Yong, Lo, Kong Mun, Hasan, Aurangzeb, Alitheen, Noorjahan Banu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269871/ https://www.ncbi.nlm.nih.gov/pubmed/23966087 http://dx.doi.org/10.3390/molecules180810042 |
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