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Chiral Peptide Nucleic Acids with a Substituent in the N-(2-Aminoethy)glycine Backbone

A peptide nucleic acid (PNA) is a synthetic nucleic acid mimic in which the sugar-phosphate backbone is replaced by a peptide backbone. PNAs hybridize to complementary DNA and RNA with higher affinity and superior sequence selectivity compared to DNA. PNAs are resistant to nucleases and proteases an...

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Detalles Bibliográficos
Autores principales:	Sugiyama, Toru, Kittaka, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269907/ https://www.ncbi.nlm.nih.gov/pubmed/23271467 http://dx.doi.org/10.3390/molecules18010287

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