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Antioxidants Improve the Phenotypes of Dilated Cardiomyopathy and Muscle Fatigue in Mitochondrial Superoxide Dismutase-Deficient Mice

Redox imbalance elevates the reactive oxygen species (ROS) level in cells and promotes age-related diseases. Superoxide dismutases (SODs) are antioxidative enzymes that catalyze the degradation of ROS. There are three SOD isoforms: SOD1/CuZn-SOD, SOD2/Mn-SOD, and SOD3/EC-SOD. SOD2, which is localize...

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Detalles Bibliográficos
Autores principales:	Koyama, Hirofumi, Nojiri, Hidetoshi, Kawakami, Satoru, Sunagawa, Tadahiro, Shirasawa, Takuji, Shimizu, Takahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269947/ https://www.ncbi.nlm.nih.gov/pubmed/23348992 http://dx.doi.org/10.3390/molecules18021383

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