Cargando…

Total Flavonoids of Scutellaria barbata Inhibit Invasion of Hepatocarcinoma via MMP/TIMP in Vitro

Metastasis is the major cause of cancer-related deaths. Targeting the process of metastasis has been proposed as a strategy to fight cancer. Scutellaria barbata D. Don (S. barbata), a traditional Chinese medicine, is used for treatment of many diseases, including cancer. This study aimed to determin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dai, Zhi-Jun, Wang, Bao-Feng, Lu, Wang-Feng, Wang, Zhi-Dong, Ma, Xiao-Bin, Min, Wei-Li, Kang, Hua-Feng, Wang, Xi-Jing, Wu, Wen-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269956/ https://www.ncbi.nlm.nih.gov/pubmed/23344202 http://dx.doi.org/10.3390/molecules18010934

Ejemplares similares

Anti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don
por: Dai, Zhi-Jun, et al.
Publicado: (2013)

Comparative Genome Analysis of Scutellaria baicalensis and Scutellaria barbata Reveals the Evolution of Active Flavonoid Biosynthesis
por: Xu, Zhichao, et al.
Publicado: (2020)

Two New Phenols from Scutellaria barbata
por: Wang, Gang, et al.
Publicado: (2011)

Scutellaria barbata flavonoids alleviate memory deficits and neuronal injuries induced by composited Aβ in rats
por: Wu, Xiao G., et al.
Publicado: (2016)

Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice
por: Gong, Tao, et al.
Publicado: (2015)

Study on the mechanism of action of Scutellaria barbata on hepatocellular carcinoma based on network pharmacology and bioinformatics
por: Yang, An-Yin, et al.
Publicado: (2023)

Scutellaria barbata Inhibits Hepatocellular Carcinoma Tumorigenicity by Inducing Ferroptosis of Hepatocellular Carcinoma Cells
por: Li, Yue, et al.
Publicado: (2022)

The complete chloroplast genome of Scutellaria barbata D. Don 1825 revealed the phylogenetic relationships of the Scutellaria genus
por: Pan, Shouhui, et al.
Publicado: (2023)

Inhibition effects of total flavonoids from Scutellaria barbata D. Don on human breast carcinoma bone metastasis via downregulating PTHrP pathway
por: Zheng, Xiao, et al.
Publicado: (2018)

Identification of Flavonoids from Scutellaria barbata D. Don as Inhibitors of HIV-1 and Cathepsin L Proteases and Their Structure–Activity Relationships
por: Tang, Ting-Ting, et al.
Publicado: (2023)

In Vitro and In Vivo Antitumor Activity of Scutellaria barbate Extract on Murine Liver Cancer
por: Dai, Zhi-Jun, et al.
Publicado: (2011)

Using the Chinese herb Scutellaria barbata against extensively drug-resistant Acinetobacter baumannii infections: in vitro and in vivo studies
por: Tsai, Chin-Chuan, et al.
Publicado: (2018)

Systematic Investigation of Scutellariae Barbatae Herba for Treating Hepatocellular Carcinoma Based on Network Pharmacology
por: Gong, Benjiao, et al.
Publicado: (2018)

Transcriptomic Insight into Terpenoid Biosynthesis and Functional Characterization of Three Diterpene Synthases in Scutellaria barbata
por: Zhang, Huabei, et al.
Publicado: (2018)

The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells
por: Chen, Chin-Chuan, et al.
Publicado: (2017)

Molecular Assessment of Scutellaria barbata D. Don in the Treatment of Nasopharyngeal Carcinoma Based on Network Pharmacology and Experimental Verification
por: Shi, Hongjian, et al.
Publicado: (2022)

Investigating the Mechanism of Scutellariae barbata Herba in the Treatment of Colorectal Cancer by Network Pharmacology and Molecular Docking
por: Qi, Xiangjun, et al.
Publicado: (2021)

Hedyotis diffusa plus Scutellaria barbata Induce Bladder Cancer Cell Apoptosis by Inhibiting Akt Signaling Pathway through Downregulating miR-155 Expression
por: Pan, Li-Tao, et al.
Publicado: (2016)

A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis
por: Wang, Zi-Long, et al.
Publicado: (2018)

Functional components in Scutellaria barbata D. Don with anti-inflammatory activity on RAW 264.7 cells
por: Liu, Hsin-Lan, et al.
Publicado: (2017)

Comparative research on stability of baicalin and baicalein administrated in monomer and total flavonoid fraction form of Radix scutellariae in biological fluids in vitro
por: Feng, Zhiqiang, et al.
Publicado: (2017)

Network pharmacology-based strategy to investigate the active ingredients and molecular mechanisms of Scutellaria Barbata D. Don against radiation pneumonitis
por: Sun, Ping-Yi, et al.
Publicado: (2021)

Molecular Targets and Mechanisms of Hedyotis diffusa-Scutellaria barbata Herb Pair for the Treatment of Colorectal Cancer Based on Network Pharmacology and Molecular Docking
por: Yang, Zhenpeng, et al.
Publicado: (2022)

Extraction Optimization, Structural Characterization, and Anti-Hepatoma Activity of Acidic Polysaccharides From Scutellaria barbata D. Don
por: Su, Wenwen, et al.
Publicado: (2022)

Optimization of the extraction of total flavonoids from Scutellaria baicalensis Georgi using the response surface methodology
por: Liu, Yanqing, et al.
Publicado: (2014)

The Flavonoid Components of Scutellaria baicalensis: Biopharmaceutical Properties and their Improvement using Nanoformulation Techniques
por: Wang, Jilin, et al.
Publicado: (2023)

A Novel Systems Pharmacology Method to Investigate Molecular Mechanisms of Scutellaria barbata D. Don for Non-small Cell Lung Cancer
por: Liu, Jianling, et al.
Publicado: (2018)

Scutellaria barbata polysaccharides inhibit tumor growth and affect the serum proteomic profiling of hepatoma H22-bearing mice
por: Li, Li, et al.
Publicado: (2019)

AURKB, CHEK1 and NEK2 as the Potential Target Proteins of Scutellaria barbata on Hepatocellular Carcinoma: An Integrated Bioinformatics Analysis
por: Huang, Chaoyuan, et al.
Publicado: (2021)

Scutellaria barbata D. Don Polysaccharides Inhibit High Glucose-Induced Proliferation and Angiogenesis of Retinal Vascular Endothelial Cells
por: Li, Wenjun, et al.
Publicado: (2021)

Scutellaria barbata D.Don (SBD) extracts suppressed tumor growth, metastasis and angiogenesis in Prostate cancer via PI3K/Akt pathway
por: Sheng, Dongya, et al.
Publicado: (2022)

Expression and Roles of MMP-2, MMP-9, MMP-13, TIMP-1, and TIMP-2 in Allergic Nasal Mucosa
por: Mori, Sachiko, et al.
Publicado: (2012)

Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas
por: Meneses-García, Abelardo, et al.
Publicado: (2008)

Scutellaria barbata D. Don Inhibits Tumor Angiogenesis via Suppression of Hedgehog Pathway in a Mouse Model of Colorectal Cancer
por: Wei, Lihui, et al.
Publicado: (2012)

Specific Flavonoids and Their Biosynthetic Pathway in Scutellaria baicalensis
por: Pei, Tianlin, et al.
Publicado: (2022)

Assessment of RANTES, MIP4A, MMP7, MMP9, MMP14, TIMP 1, TIMP 2 and TIMP 3 concentration in the follicular fluid of patients undergoing in vitro fertilization/embryo transfer procedure
por: Adamczak, Rafał, et al.
Publicado: (2023)

Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways
por: Chen, Guang-Yao, et al.
Publicado: (2021)

Evaluation of MMP-9 and MMP-2 and their suppressor TIMP-1 and TIMP-2 in adenocarcinoma of esophagogastric junction
por: Lu, Xiaofei, et al.
Publicado: (2016)

Ursolic Acid Ameliorated Neuronal Damage by Restoring Microglia-Activated MMP/TIMP Imbalance in vitro
por: Qiu, Luying, et al.
Publicado: (2023)

Stepwise Diagnostic Product Ions Filtering Strategy for Rapid Discovery of Diterpenoids in Scutellaria barbata Based on UHPLC-Q-Exactive-Orbitrap-MS
por: Zhou, Xinhua, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_irnm490tj1dlvkf8619f3bgnso