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Unexpected Behavior of Enaminones: Interesting New Routes to 1,6-Naphthyridines, 2-Oxopyrrolidines and Pyrano[4,3,2-de][1,6]naphthyridines

Reaction of enaminones 1a–d with 2-aminoprop-1-ene-1,1,3-tricarbonitrile (2) in the presence of AcOH/NH(4)OAc afforded 7-amino-5-oxo-5,6-dihydro-1,6-naphthyridine-8-carbonitrile derivatives 9a–d. On the other hand, 2-aminopyrano[4,3,2-de][1,6]naphthyridine-3-carbonitriles 20a–c,e were the only obtai...

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Detalles Bibliográficos
Autores principales: Moustafa, Moustafa Sherief, Al-Mousawi, Saleh Mohammed, Hilmy, Noha Mohamed, Ibrahim, Yehia A., Liermann, Johannes C., Meier, Herbert, Elnagdi, Mohamed Hilmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270018/
https://www.ncbi.nlm.nih.gov/pubmed/23271466
http://dx.doi.org/10.3390/molecules18010276