Synthesis and Antimicrobial Activity of Novel Substituted Ethyl 2-(Quinolin-4-yl)-propanoates

Substituted 4-hydroxyquinolines were synthesized from anilines and diethyl 2-(ethoxymethylene)malonate by the Gould-Jacobs reaction via cyclization of the intermediate anilinomethylenemalonate followed by hydrolysis and decarboxylation. The 4-hydroxyquinolines reacted with phosphorous oxychloride to...

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Detalles Bibliográficos
Autores principales: Khan, M. Akram, Miller, Keith, Rainsford, Kim Drummond, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270033/
https://www.ncbi.nlm.nih.gov/pubmed/23486102
http://dx.doi.org/10.3390/molecules18033227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270033/
https://www.ncbi.nlm.nih.gov/pubmed/23486102
http://dx.doi.org/10.3390/molecules18033227

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