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GABA(B)-Agonistic Activity of Certain Baclofen Homologues

Baclofen (1) is a potent and selective agonist for bicuculline-insensitive GABA(B) receptors and is used clinically as an antispastic and muscle relaxant agent. In the search for new bioactive chemical entities that bind specifically to GABA(B) receptors, we report here the synthesis of certain bacl...

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Detalles Bibliográficos
Autores principales:	Attia, Mohamed I., Herdeis, Claus, Bräuner-Osborne, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270091/ https://www.ncbi.nlm.nih.gov/pubmed/23973998 http://dx.doi.org/10.3390/molecules180910266

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