Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain

Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. Th...

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Detalles Bibliográficos
Autores principales: Wang, Mei Ling, Lu, Chun Hua, Xu, Qing Yan, Song, Si Yang, Hu, Zhi Yu, Zheng, Zhong Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270126/
https://www.ncbi.nlm.nih.gov/pubmed/23681057
http://dx.doi.org/10.3390/molecules18055723
Descripción
Sumario:Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. The new compounds showed modest cytotoxic activity against HepG-2 cell line and weak antimicrobial activity against Staphylococcus aureus.

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