Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain

Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. Th...

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Autores principales: Wang, Mei Ling, Lu, Chun Hua, Xu, Qing Yan, Song, Si Yang, Hu, Zhi Yu, Zheng, Zhong Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270126/
https://www.ncbi.nlm.nih.gov/pubmed/23681057
http://dx.doi.org/10.3390/molecules18055723
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author Wang, Mei Ling
Lu, Chun Hua
Xu, Qing Yan
Song, Si Yang
Hu, Zhi Yu
Zheng, Zhong Hui
author_facet Wang, Mei Ling
Lu, Chun Hua
Xu, Qing Yan
Song, Si Yang
Hu, Zhi Yu
Zheng, Zhong Hui
author_sort Wang, Mei Ling
collection PubMed
description Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. The new compounds showed modest cytotoxic activity against HepG-2 cell line and weak antimicrobial activity against Staphylococcus aureus.
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spelling pubmed-62701262018-12-14 Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain Wang, Mei Ling Lu, Chun Hua Xu, Qing Yan Song, Si Yang Hu, Zhi Yu Zheng, Zhong Hui Molecules Article Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds. Their structures were elucidated by spectroscopic and chemical methods. The new compounds showed modest cytotoxic activity against HepG-2 cell line and weak antimicrobial activity against Staphylococcus aureus. MDPI 2013-05-16 /pmc/articles/PMC6270126/ /pubmed/23681057 http://dx.doi.org/10.3390/molecules18055723 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wang, Mei Ling
Lu, Chun Hua
Xu, Qing Yan
Song, Si Yang
Hu, Zhi Yu
Zheng, Zhong Hui
Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain
title Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain
title_full Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain
title_fullStr Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain
title_full_unstemmed Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain
title_short Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain
title_sort four new citrinin derivatives from a marine-derived penicillium sp. fungal strain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270126/
https://www.ncbi.nlm.nih.gov/pubmed/23681057
http://dx.doi.org/10.3390/molecules18055723
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