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In Vitro and in Vivo Anticancer Activity of Aconitine on Melanoma Cell Line B16

The anti-tumor effect of aconitine in melanoma cell line B16 has been studied in this paper. We found that B16 cells showed significantly reduced growth rates and increased apoptotic effects in the presence of aconitine. Furthermore, aconitine inhibited the PI3K/AKT and MAPK/ERK1/2 signaling pathway...

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Detalles Bibliográficos
Autores principales:	Du, Juan, Lu, Xiaonian, Long, Ziwen, Zhang, Zhen, Zhu, Xiaohua, Yang, Yongsheng, Xu, Jinhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270132/ https://www.ncbi.nlm.nih.gov/pubmed/23299553 http://dx.doi.org/10.3390/molecules18010757

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