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Understanding Acid Lability of Cysteine Protecting Groups
Cys-disulfide bonds contribute to the stabilization of peptide and protein structures. The synthesis of these molecules requires a proper protection of Cys residues, which is crucial to prevent side-reactions and also to achieve the correct Cys connectivity. Here we undertook a mechanistic study of...
Autores principales: | Ramos-Tomillero, Iván, Mendive-Tapia, Lorena, Góngora-Benítez, Miriam, Nicolás, Ernesto, Tulla-Puche, Judit, Albericio, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270164/ https://www.ncbi.nlm.nih.gov/pubmed/23648593 http://dx.doi.org/10.3390/molecules18055155 |
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