Cargando…

Two New Sphingolipids from the Leaves of Piper betle L.

Two new sphingolipids, pipercerebrosides A (1) and B (2), were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against t...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Duo-Zhi, Xiong, Hua-Bin, Tian, Kai, Guo, Jun-Ming, Huang, Xiang-Zhong, Jiang, Zhi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270174/
https://www.ncbi.nlm.nih.gov/pubmed/24036513
http://dx.doi.org/10.3390/molecules180911241
_version_ 1783376637005398016
author Chen, Duo-Zhi
Xiong, Hua-Bin
Tian, Kai
Guo, Jun-Ming
Huang, Xiang-Zhong
Jiang, Zhi-Yong
author_facet Chen, Duo-Zhi
Xiong, Hua-Bin
Tian, Kai
Guo, Jun-Ming
Huang, Xiang-Zhong
Jiang, Zhi-Yong
author_sort Chen, Duo-Zhi
collection PubMed
description Two new sphingolipids, pipercerebrosides A (1) and B (2), were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against the cancer cell lines K562 and HL-60 in a MTT assay.
format Online
Article
Text
id pubmed-6270174
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62701742018-12-18 Two New Sphingolipids from the Leaves of Piper betle L. Chen, Duo-Zhi Xiong, Hua-Bin Tian, Kai Guo, Jun-Ming Huang, Xiang-Zhong Jiang, Zhi-Yong Molecules Article Two new sphingolipids, pipercerebrosides A (1) and B (2), were isolated from the leaves of Piper betle L. Their structures, including absolute configurations, were determined by spectroscopic analysis and chemical degradation. These two compounds did not show significant cytotoxic activity against the cancer cell lines K562 and HL-60 in a MTT assay. MDPI 2013-09-12 /pmc/articles/PMC6270174/ /pubmed/24036513 http://dx.doi.org/10.3390/molecules180911241 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Chen, Duo-Zhi
Xiong, Hua-Bin
Tian, Kai
Guo, Jun-Ming
Huang, Xiang-Zhong
Jiang, Zhi-Yong
Two New Sphingolipids from the Leaves of Piper betle L.
title Two New Sphingolipids from the Leaves of Piper betle L.
title_full Two New Sphingolipids from the Leaves of Piper betle L.
title_fullStr Two New Sphingolipids from the Leaves of Piper betle L.
title_full_unstemmed Two New Sphingolipids from the Leaves of Piper betle L.
title_short Two New Sphingolipids from the Leaves of Piper betle L.
title_sort two new sphingolipids from the leaves of piper betle l.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270174/
https://www.ncbi.nlm.nih.gov/pubmed/24036513
http://dx.doi.org/10.3390/molecules180911241
work_keys_str_mv AT chenduozhi twonewsphingolipidsfromtheleavesofpiperbetlel
AT xionghuabin twonewsphingolipidsfromtheleavesofpiperbetlel
AT tiankai twonewsphingolipidsfromtheleavesofpiperbetlel
AT guojunming twonewsphingolipidsfromtheleavesofpiperbetlel
AT huangxiangzhong twonewsphingolipidsfromtheleavesofpiperbetlel
AT jiangzhiyong twonewsphingolipidsfromtheleavesofpiperbetlel