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Synthesis and Anti-HBV Activity of Novel 3′-N-phenylsulfonyl Docetaxel Analogs
Nine new 3′-N-phenylsulfonyl docetaxel analogs were synthesized in good yields from the key intermediate N-phenylsulfonyl oxazolidine via a six-step route. These analogs were tested for anti-hepatitis B virus (HBV) activity in vitro. Compounds 3e, 3g and 3j showed more potent inhibitory activity aga...
Autores principales: | Chang, Jun, Hao, Yun-Peng, Hao, Xiao-Dong, Lu, Hong-Fu, Yu, Jian-Ming, Sun, Xun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270178/ https://www.ncbi.nlm.nih.gov/pubmed/23973993 http://dx.doi.org/10.3390/molecules180910189 |
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