A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii

A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mai...

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Detalles Bibliográficos
Autores principales: Zhang, Yu-Mei, Xu, Jian, Xiao, Lin, Zeng, Guang-Zhi, Sun, Zhang-Hua, Tan, Ning-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270199/
https://www.ncbi.nlm.nih.gov/pubmed/23334571
http://dx.doi.org/10.3390/molecules18011255
Descripción
Sumario:A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5–11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC(50) values were 6.9, 29.7 and 52.9 μM, respectively.

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