A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii

A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mai...

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Autores principales: Zhang, Yu-Mei, Xu, Jian, Xiao, Lin, Zeng, Guang-Zhi, Sun, Zhang-Hua, Tan, Ning-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270199/
https://www.ncbi.nlm.nih.gov/pubmed/23334571
http://dx.doi.org/10.3390/molecules18011255
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author Zhang, Yu-Mei
Xu, Jian
Xiao, Lin
Zeng, Guang-Zhi
Sun, Zhang-Hua
Tan, Ning-Hua
author_facet Zhang, Yu-Mei
Xu, Jian
Xiao, Lin
Zeng, Guang-Zhi
Sun, Zhang-Hua
Tan, Ning-Hua
author_sort Zhang, Yu-Mei
collection PubMed
description A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5–11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC(50) values were 6.9, 29.7 and 52.9 μM, respectively.
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spelling pubmed-62701992018-12-14 A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii Zhang, Yu-Mei Xu, Jian Xiao, Lin Zeng, Guang-Zhi Sun, Zhang-Hua Tan, Ning-Hua Molecules Article A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2–11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5–11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC(50) values were 6.9, 29.7 and 52.9 μM, respectively. MDPI 2013-01-18 /pmc/articles/PMC6270199/ /pubmed/23334571 http://dx.doi.org/10.3390/molecules18011255 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zhang, Yu-Mei
Xu, Jian
Xiao, Lin
Zeng, Guang-Zhi
Sun, Zhang-Hua
Tan, Ning-Hua
A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
title A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
title_full A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
title_fullStr A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
title_full_unstemmed A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
title_short A New Phenolic Glycoside from Chamaecyparis obtusa var. breviramea f. crippsii
title_sort new phenolic glycoside from chamaecyparis obtusa var. breviramea f. crippsii
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270199/
https://www.ncbi.nlm.nih.gov/pubmed/23334571
http://dx.doi.org/10.3390/molecules18011255
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