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Schizandrin Protects Primary Rat Cortical Cell Cultures from Glutamate-Induced Apoptosis by Inhibiting Activation of the MAPK Family and the Mitochondria Dependent Pathway
Glutamate-induced excitotoxicity has been implicated in a variety of neuronal degenerative disorders. In the present study, we investigated the possible neuroprotective effects of schizandrin against apoptosis of primary cultured rat cortical cells induced by glutamate. Glutamate (10 μM) administere...
Autores principales: | Lee, Meng-Shiou, Chao, Jung, Yen, Jiin-Cherng, Lin, Li-Wei, Tsai, Fan-Shiu, Hsieh, Ming-Tsuen, Peng, Wen-Huang, Cheng, Hao-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270204/ https://www.ncbi.nlm.nih.gov/pubmed/23271470 http://dx.doi.org/10.3390/molecules18010354 |
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