Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives

Tyrosinase enzyme is a monophenol monoxygenase enzyme, which plays an important role in human as a rate limiting step enzyme for different specific metabolic pathways, as well as its useful application in industry and agriculture. So this study was carried out to test the effect of newly prepared co...

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Detalles Bibliográficos
Autores principales: El Sadek, Mohamed M., Hassan, Seham Y., Abdelwahab, Huda E., Yacout, Galila A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270226/
https://www.ncbi.nlm.nih.gov/pubmed/23877049
http://dx.doi.org/10.3390/molecules18078550
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author El Sadek, Mohamed M.
Hassan, Seham Y.
Abdelwahab, Huda E.
Yacout, Galila A.
author_facet El Sadek, Mohamed M.
Hassan, Seham Y.
Abdelwahab, Huda E.
Yacout, Galila A.
author_sort El Sadek, Mohamed M.
collection PubMed
description Tyrosinase enzyme is a monophenol monoxygenase enzyme, which plays an important role in human as a rate limiting step enzyme for different specific metabolic pathways, as well as its useful application in industry and agriculture. So this study was carried out to test the effect of newly prepared compounds containing 1,3,4-oxadiazoles with different substituted groups on tyrosinase enzyme activity, hoping to use them in the treatment of some diseases arising from tyrosinase activity disorders such as Parkinson’s disease, schizophrenia, autism, attention deficit, hyperactivity disorder, and cancer.
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spelling pubmed-62702262018-12-17 Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives El Sadek, Mohamed M. Hassan, Seham Y. Abdelwahab, Huda E. Yacout, Galila A. Molecules Article Tyrosinase enzyme is a monophenol monoxygenase enzyme, which plays an important role in human as a rate limiting step enzyme for different specific metabolic pathways, as well as its useful application in industry and agriculture. So this study was carried out to test the effect of newly prepared compounds containing 1,3,4-oxadiazoles with different substituted groups on tyrosinase enzyme activity, hoping to use them in the treatment of some diseases arising from tyrosinase activity disorders such as Parkinson’s disease, schizophrenia, autism, attention deficit, hyperactivity disorder, and cancer. MDPI 2013-07-19 /pmc/articles/PMC6270226/ /pubmed/23877049 http://dx.doi.org/10.3390/molecules18078550 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
El Sadek, Mohamed M.
Hassan, Seham Y.
Abdelwahab, Huda E.
Yacout, Galila A.
Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives
title Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives
title_full Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives
title_fullStr Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives
title_full_unstemmed Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives
title_short Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives
title_sort synthesis and bioassay of a new class of furanyl-1,3,4-oxadiazole derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270226/
https://www.ncbi.nlm.nih.gov/pubmed/23877049
http://dx.doi.org/10.3390/molecules18078550
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