Cargando…

The Ameliorative Effects of l-2-Oxothiazolidine-4-Carboxylate on Acetaminophen-Induced Hepatotoxicity in Mice

The aim of the study was to investigate the ameliorative effects and the mechanism of action of l-2-oxothiazolidine-4-carboxylate (OTC) on acetaminophen (APAP)-induced hepatotoxicity in mice. Mice were randomly divided into six groups: normal control group, APAP only treated group, APAP + 25 mg/kg O...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Jiwon, Park, Kwang-Hyun, Kim, Sung Zoo, Shin, Jun Ho, Jang, Seon-Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270228/ https://www.ncbi.nlm.nih.gov/pubmed/23507776 http://dx.doi.org/10.3390/molecules18033467

Ejemplares similares

L-2-oxothiazolidine-4-carboxylic acid attenuates oxidative stress and inflammation in retinal pigment epithelium
por: Promsote, Wanwisa, et al.
Publicado: (2014)

Protective Effects of L-2-Oxothiazolidine-4-Carboxylate during Isoproterenol-Induced Myocardial Infarction in Rats: In Vivo Study
por: Angelovski, Marija, et al.
Publicado: (2022)

Protective Effects of Apamin on Acetaminophen-Induced Hepatotoxicity in Mice
por: Jang, Hyo-Jeong, et al.
Publicado: (2023)

Silymarin prevents acetaminophen-induced hepatotoxicity in mice
por: Papackova, Zuzana, et al.
Publicado: (2018)

Redox Nanoparticle Therapeutics for Acetaminophen-Induced Hepatotoxicity in Mice
por: Boonruamkaew, Phetcharat, et al.
Publicado: (2016)

Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice
por: Barman, P K, et al.
Publicado: (2016)

Fructose diet alleviates acetaminophen-induced hepatotoxicity in mice
por: Cho, Sungjoon, et al.
Publicado: (2017)

Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice
por: Sriphoosanaphan, Supachaya, et al.
Publicado: (2023)

Impact of malnourishment on the pharmacokinetics of acetaminophen and susceptibility to acetaminophen hepatotoxicity
por: Zillen, Daan, et al.
Publicado: (2021)

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity
por: Ghallab, Ahmed, et al.
Publicado: (2022)

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity
por: Hur, Kyu Yeon, et al.
Publicado: (2012)

Study of the Protective Effect of Teucrium polium L. Extract on Acetaminophen-Induced Hepatotoxicity in Mice
por: Forouzandeh, Hossein, et al.
Publicado: (2013)

Hepatoprotective and Antioxidative Activities of Cornus officinalis against Acetaminophen-Induced Hepatotoxicity in Mice
por: Lee, Nam-Hun, et al.
Publicado: (2012)

An Amino Acids Mixture Improves the Hepatotoxicity Induced by Acetaminophen in Mice
por: Di Pierro, Francesco, et al.
Publicado: (2013)

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice
por: Yoshioka, Hiroki, et al.
Publicado: (2017)

Evaluation of the Protective Effects of Doxycycline on Acetaminophen-Induced Hepatotoxicity in Mice
por: Soltani, Shirin, et al.
Publicado: (2019)

Mitochondrial–Lysosomal Axis in Acetaminophen Hepatotoxicity
por: Moles, Anna, et al.
Publicado: (2018)

Role of Pyroptosis in Acetaminophen-Induced Hepatotoxicity
por: Jaeschke, Hartmut, et al.
Publicado: (2022)

Regeneration and Recovery after Acetaminophen Hepatotoxicity
por: Bhushan, Bharat, et al.
Publicado: (2023)

Extract of Triticum aestivum Sprouts Suppresses Acetaminophen-Induced Hepatotoxicity in Mice by Inhibiting Oxidative Stress
por: Lim, Ji-Ye, et al.
Publicado: (2021)

Recent Updates on Acetaminophen Hepatotoxicity: The Role of Nrf2 in Hepatoprotection
por: Gum, Sang Il, et al.
Publicado: (2013)

Acetaminophen Hepatotoxicity: Not as Simple as One Might Think! Introductory Comments on the Special Issue—Recent Advances in Acetaminophen Hepatotoxicity
por: Jaeschke, Hartmut
Publicado: (2022)

Gene Expression in Rat Hearts Following Oral Administration of a Single Hepatotoxic Dose of Acetaminophen
por: Jin, Seon Mi, et al.
Publicado: (2012)

Effects of α-Melanocortin Enantiomers on Acetaminophen-Induced Hepatotoxicity in CBA Mice
por: Turčić, Petra, et al.
Publicado: (2009)

Mitochondrial Glrx2 Knockout Augments Acetaminophen-Induced Hepatotoxicity in Mice
por: Li, Jing, et al.
Publicado: (2022)

Characteristics and Outcomes of Acetaminophen Overdose and Hepatotoxicity in Thailand
por: Pholmoo, Natthiya, et al.
Publicado: (2019)

Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology
por: Ramachandran, Anup, et al.
Publicado: (2017)

Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update
por: Yoon, Eric, et al.
Publicado: (2016)

Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen
por: Šrajer Gajdošik, Martina, et al.
Publicado: (2022)

Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity
por: Prather, Benjamin L., et al.
Publicado: (2023)

Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice
por: Ding, Yi, et al.
Publicado: (2016)

Protective Effects of Interleukin-37 Expression against Acetaminophen-Induced Hepatotoxicity in Mice
por: Xu, Zhiwei, et al.
Publicado: (2022)

Acetaminophen Induced Hepatotoxicity in Wistar Rats—A Proteomic Approach
por: Ilavenil, Soundharrajan, et al.
Publicado: (2016)

The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model
por: Ben-Shachar, Rotem, et al.
Publicado: (2012)

Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity
por: Amaral, Sylvia S, et al.
Publicado: (2013)

Emerging novel therapies against paracetamol (acetaminophen) hepatotoxicity
por: Jaeschke, Hartmut
Publicado: (2019)

Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice
por: Knight, Tamara R, et al.
Publicado: (2004)

Protective effects of natsumikan (Citrus natsudaidai) extract on acetaminophen-induced lethal hepatotoxicity in mice
por: Yamaura, Katsunori, et al.
Publicado: (2012)

Protective Effect of Gemfibrozil on Hepatotoxicity Induced by Acetaminophen in Mice: the Importance of Oxidative Stress Suppression
por: Nikravesh, Hojatolla, et al.
Publicado: (2018)

Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice
por: Schuran, Fenja A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k2u0ff8tt7bu2kd05g00nd7j4q