Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions

An efficient method has been developed for the synthesis of β-enaminones under solvent-free reaction conditions using PPA-SiO(2) as catalyst. The reaction yields were good to excellent (up to 90%). This methodology affords high selectivity and good tolerance of a variety of different functional grou...

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Detalles Bibliográficos
Autores principales: Nisar, Muhammad, Ali, Ihsan, Shah, Muhammad Raza, Qayum, Mughal, Zia-Ul-Haq, Muhammad, Rashid, Umer, Islam, Md. Saiful
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270262/
https://www.ncbi.nlm.nih.gov/pubmed/24335572
http://dx.doi.org/10.3390/molecules181215182
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author Nisar, Muhammad
Ali, Ihsan
Shah, Muhammad Raza
Qayum, Mughal
Zia-Ul-Haq, Muhammad
Rashid, Umer
Islam, Md. Saiful
author_facet Nisar, Muhammad
Ali, Ihsan
Shah, Muhammad Raza
Qayum, Mughal
Zia-Ul-Haq, Muhammad
Rashid, Umer
Islam, Md. Saiful
author_sort Nisar, Muhammad
collection PubMed
description An efficient method has been developed for the synthesis of β-enaminones under solvent-free reaction conditions using PPA-SiO(2) as catalyst. The reaction yields were good to excellent (up to 90%). This methodology affords high selectivity and good tolerance of a variety of different functional groups present on both aromatic and aliphatic amines. In addition, the methodology is environmentally benign and cost-effective due to absence of solvent and easy work-up.
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spelling pubmed-62702622018-12-20 Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions Nisar, Muhammad Ali, Ihsan Shah, Muhammad Raza Qayum, Mughal Zia-Ul-Haq, Muhammad Rashid, Umer Islam, Md. Saiful Molecules Communication An efficient method has been developed for the synthesis of β-enaminones under solvent-free reaction conditions using PPA-SiO(2) as catalyst. The reaction yields were good to excellent (up to 90%). This methodology affords high selectivity and good tolerance of a variety of different functional groups present on both aromatic and aliphatic amines. In addition, the methodology is environmentally benign and cost-effective due to absence of solvent and easy work-up. MDPI 2013-12-10 /pmc/articles/PMC6270262/ /pubmed/24335572 http://dx.doi.org/10.3390/molecules181215182 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Nisar, Muhammad
Ali, Ihsan
Shah, Muhammad Raza
Qayum, Mughal
Zia-Ul-Haq, Muhammad
Rashid, Umer
Islam, Md. Saiful
Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions
title Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions
title_full Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions
title_fullStr Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions
title_full_unstemmed Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions
title_short Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions
title_sort efficient ppa-sio(2)-catalyzed synthesis of β-enaminones under solvent-free conditions
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270262/
https://www.ncbi.nlm.nih.gov/pubmed/24335572
http://dx.doi.org/10.3390/molecules181215182
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