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Accidental Interaction between PDZ Domains and Diclofenac Revealed by NMR-Assisted Virtual Screening

In silico approaches have become indispensable for drug discovery as well as drug repositioning and adverse effect prediction. We have developed the eF-seek program to predict protein–ligand interactions based on the surface structure of proteins using a clique search algorithm. We have also develop...

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Detalles Bibliográficos
Autores principales:	Tenno, Takeshi, Goda, Natsuko, Umetsu, Yoshitaka, Ota, Motonori, Kinoshita, Kengo, Hiroaki, Hidekazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270271/ https://www.ncbi.nlm.nih.gov/pubmed/23966078 http://dx.doi.org/10.3390/molecules18089567

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