Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity

A HPLC-ESI-IT-MS(n) method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P....

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Detalles Bibliográficos
Autores principales: Zanutto, Fabiana Volpe, Boldrin, Paula Karina, Varanda, Eliana Aparecida, de Souza, Samara Fernandes, Sano, Paulo Takeo, Vilegas, Wagner, dos Santos, Lourdes Campaner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270276/
https://www.ncbi.nlm.nih.gov/pubmed/23271464
http://dx.doi.org/10.3390/molecules18010244
Descripción
Sumario:A HPLC-ESI-IT-MS(n) method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.

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