Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity

A HPLC-ESI-IT-MS(n) method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P....

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Autores principales: Zanutto, Fabiana Volpe, Boldrin, Paula Karina, Varanda, Eliana Aparecida, de Souza, Samara Fernandes, Sano, Paulo Takeo, Vilegas, Wagner, dos Santos, Lourdes Campaner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270276/
https://www.ncbi.nlm.nih.gov/pubmed/23271464
http://dx.doi.org/10.3390/molecules18010244
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author Zanutto, Fabiana Volpe
Boldrin, Paula Karina
Varanda, Eliana Aparecida
de Souza, Samara Fernandes
Sano, Paulo Takeo
Vilegas, Wagner
dos Santos, Lourdes Campaner
author_facet Zanutto, Fabiana Volpe
Boldrin, Paula Karina
Varanda, Eliana Aparecida
de Souza, Samara Fernandes
Sano, Paulo Takeo
Vilegas, Wagner
dos Santos, Lourdes Campaner
author_sort Zanutto, Fabiana Volpe
collection PubMed
description A HPLC-ESI-IT-MS(n) method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.
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spelling pubmed-62702762018-12-14 Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity Zanutto, Fabiana Volpe Boldrin, Paula Karina Varanda, Eliana Aparecida de Souza, Samara Fernandes Sano, Paulo Takeo Vilegas, Wagner dos Santos, Lourdes Campaner Molecules Article A HPLC-ESI-IT-MS(n) method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a. MDPI 2012-12-27 /pmc/articles/PMC6270276/ /pubmed/23271464 http://dx.doi.org/10.3390/molecules18010244 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zanutto, Fabiana Volpe
Boldrin, Paula Karina
Varanda, Eliana Aparecida
de Souza, Samara Fernandes
Sano, Paulo Takeo
Vilegas, Wagner
dos Santos, Lourdes Campaner
Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity
title Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity
title_full Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity
title_fullStr Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity
title_full_unstemmed Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity
title_short Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MS(n) and Their Mutagenic Activity
title_sort characterization of flavonoids and naphthopyranones in methanol extracts of paepalanthus chiquitensis herzog by hplc-esi-it-ms(n) and their mutagenic activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270276/
https://www.ncbi.nlm.nih.gov/pubmed/23271464
http://dx.doi.org/10.3390/molecules18010244
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