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Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12

Two spirobisnaphthalenes, namely palmarumycins C(2) and C(3), were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C(2) and C(3) were...

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Autores principales: Mou, Yan, Meng, Jiajia, Fu, Xiaoxiang, Wang, Xiaohan, Tian, Jin, Wang, Mingan, Peng, Youliang, Zhou, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270283/
https://www.ncbi.nlm.nih.gov/pubmed/24352015
http://dx.doi.org/10.3390/molecules181215587
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author Mou, Yan
Meng, Jiajia
Fu, Xiaoxiang
Wang, Xiaohan
Tian, Jin
Wang, Mingan
Peng, Youliang
Zhou, Ligang
author_facet Mou, Yan
Meng, Jiajia
Fu, Xiaoxiang
Wang, Xiaohan
Tian, Jin
Wang, Mingan
Peng, Youliang
Zhou, Ligang
author_sort Mou, Yan
collection PubMed
description Two spirobisnaphthalenes, namely palmarumycins C(2) and C(3), were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C(2) and C(3) were obtained as 0.40 g/L and 1.19 g/L, which were 40.00 fold and 59.50 fold higher, respectively, in comparison with those of the control (0.01 g/L and 0.02 g/L). The results indicated that addition of 1-hexadecene can be an effective strategy for enhancing the production of palmarumycins C(2) and C(3) in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Palmarumycin C(3) exhibited stronger antimicrobial and antioxidant activities than palmarumycin C(2).
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spelling pubmed-62702832018-12-20 Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 Mou, Yan Meng, Jiajia Fu, Xiaoxiang Wang, Xiaohan Tian, Jin Wang, Mingan Peng, Youliang Zhou, Ligang Molecules Article Two spirobisnaphthalenes, namely palmarumycins C(2) and C(3), were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C(2) and C(3) were obtained as 0.40 g/L and 1.19 g/L, which were 40.00 fold and 59.50 fold higher, respectively, in comparison with those of the control (0.01 g/L and 0.02 g/L). The results indicated that addition of 1-hexadecene can be an effective strategy for enhancing the production of palmarumycins C(2) and C(3) in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Palmarumycin C(3) exhibited stronger antimicrobial and antioxidant activities than palmarumycin C(2). MDPI 2013-12-13 /pmc/articles/PMC6270283/ /pubmed/24352015 http://dx.doi.org/10.3390/molecules181215587 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Mou, Yan
Meng, Jiajia
Fu, Xiaoxiang
Wang, Xiaohan
Tian, Jin
Wang, Mingan
Peng, Youliang
Zhou, Ligang
Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12
title Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12
title_full Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12
title_fullStr Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12
title_full_unstemmed Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12
title_short Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12
title_sort antimicrobial and antioxidant activities and effect of 1-hexadecene addition on palmarumycin c(2) and c(3) yields in liquid culture of endophytic fungus berkleasmium sp. dzf12
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270283/
https://www.ncbi.nlm.nih.gov/pubmed/24352015
http://dx.doi.org/10.3390/molecules181215587
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