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Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12
Two spirobisnaphthalenes, namely palmarumycins C(2) and C(3), were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C(2) and C(3) were...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270283/ https://www.ncbi.nlm.nih.gov/pubmed/24352015 http://dx.doi.org/10.3390/molecules181215587 |
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author | Mou, Yan Meng, Jiajia Fu, Xiaoxiang Wang, Xiaohan Tian, Jin Wang, Mingan Peng, Youliang Zhou, Ligang |
author_facet | Mou, Yan Meng, Jiajia Fu, Xiaoxiang Wang, Xiaohan Tian, Jin Wang, Mingan Peng, Youliang Zhou, Ligang |
author_sort | Mou, Yan |
collection | PubMed |
description | Two spirobisnaphthalenes, namely palmarumycins C(2) and C(3), were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C(2) and C(3) were obtained as 0.40 g/L and 1.19 g/L, which were 40.00 fold and 59.50 fold higher, respectively, in comparison with those of the control (0.01 g/L and 0.02 g/L). The results indicated that addition of 1-hexadecene can be an effective strategy for enhancing the production of palmarumycins C(2) and C(3) in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Palmarumycin C(3) exhibited stronger antimicrobial and antioxidant activities than palmarumycin C(2). |
format | Online Article Text |
id | pubmed-6270283 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62702832018-12-20 Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 Mou, Yan Meng, Jiajia Fu, Xiaoxiang Wang, Xiaohan Tian, Jin Wang, Mingan Peng, Youliang Zhou, Ligang Molecules Article Two spirobisnaphthalenes, namely palmarumycins C(2) and C(3), were isolated from cultures of the endophytic fungus Berkleasmium sp. Dzf12 after treatment with 1-hexadecene. After addition of 1-hexadecene at 10% to the medium on day 6 of culture, the maximal yields of palmarumycins C(2) and C(3) were obtained as 0.40 g/L and 1.19 g/L, which were 40.00 fold and 59.50 fold higher, respectively, in comparison with those of the control (0.01 g/L and 0.02 g/L). The results indicated that addition of 1-hexadecene can be an effective strategy for enhancing the production of palmarumycins C(2) and C(3) in liquid culture of endophytic fungus Berkleasmium sp. Dzf12. Palmarumycin C(3) exhibited stronger antimicrobial and antioxidant activities than palmarumycin C(2). MDPI 2013-12-13 /pmc/articles/PMC6270283/ /pubmed/24352015 http://dx.doi.org/10.3390/molecules181215587 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Mou, Yan Meng, Jiajia Fu, Xiaoxiang Wang, Xiaohan Tian, Jin Wang, Mingan Peng, Youliang Zhou, Ligang Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 |
title | Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 |
title_full | Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 |
title_fullStr | Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 |
title_full_unstemmed | Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 |
title_short | Antimicrobial and Antioxidant Activities and Effect of 1-Hexadecene Addition on Palmarumycin C(2) and C(3) Yields in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12 |
title_sort | antimicrobial and antioxidant activities and effect of 1-hexadecene addition on palmarumycin c(2) and c(3) yields in liquid culture of endophytic fungus berkleasmium sp. dzf12 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270283/ https://www.ncbi.nlm.nih.gov/pubmed/24352015 http://dx.doi.org/10.3390/molecules181215587 |
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