Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO

Yellow pigments, fomitellanols A (1a) and B (2a), and drimane-type sesquiterpenoid ethers of isocitric acid, cryptoporic acids P (3) and Q (4), have been isolated fromthe fruiting bodies of Fomitellafraxinea (Polyporaceae). Their structures were established by a combination of extensive NMR spectros...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Kazuko, Koso, Kazuaki, Shimomura, Masumi, Tanaka, Masami, Yamamoto, Hirofumi, Imagawa, Hiroshi, Arihara, Shigenobu, Hashimoto, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270288/
https://www.ncbi.nlm.nih.gov/pubmed/23571531
http://dx.doi.org/10.3390/molecules18044181
Descripción
Sumario:Yellow pigments, fomitellanols A (1a) and B (2a), and drimane-type sesquiterpenoid ethers of isocitric acid, cryptoporic acids P (3) and Q (4), have been isolated fromthe fruiting bodies of Fomitellafraxinea (Polyporaceae). Their structures were established by a combination of extensive NMR spectroscopy and/or X-ray crystallographic analyses, and their biological activity against COX-1, COX-2, and 5-LO was investigated.

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