Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO

Yellow pigments, fomitellanols A (1a) and B (2a), and drimane-type sesquiterpenoid ethers of isocitric acid, cryptoporic acids P (3) and Q (4), have been isolated fromthe fruiting bodies of Fomitellafraxinea (Polyporaceae). Their structures were established by a combination of extensive NMR spectros...

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Autores principales: Yoshikawa, Kazuko, Koso, Kazuaki, Shimomura, Masumi, Tanaka, Masami, Yamamoto, Hirofumi, Imagawa, Hiroshi, Arihara, Shigenobu, Hashimoto, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270288/
https://www.ncbi.nlm.nih.gov/pubmed/23571531
http://dx.doi.org/10.3390/molecules18044181
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author Yoshikawa, Kazuko
Koso, Kazuaki
Shimomura, Masumi
Tanaka, Masami
Yamamoto, Hirofumi
Imagawa, Hiroshi
Arihara, Shigenobu
Hashimoto, Toshihiro
author_facet Yoshikawa, Kazuko
Koso, Kazuaki
Shimomura, Masumi
Tanaka, Masami
Yamamoto, Hirofumi
Imagawa, Hiroshi
Arihara, Shigenobu
Hashimoto, Toshihiro
author_sort Yoshikawa, Kazuko
collection PubMed
description Yellow pigments, fomitellanols A (1a) and B (2a), and drimane-type sesquiterpenoid ethers of isocitric acid, cryptoporic acids P (3) and Q (4), have been isolated fromthe fruiting bodies of Fomitellafraxinea (Polyporaceae). Their structures were established by a combination of extensive NMR spectroscopy and/or X-ray crystallographic analyses, and their biological activity against COX-1, COX-2, and 5-LO was investigated.
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spelling pubmed-62702882018-12-14 Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO Yoshikawa, Kazuko Koso, Kazuaki Shimomura, Masumi Tanaka, Masami Yamamoto, Hirofumi Imagawa, Hiroshi Arihara, Shigenobu Hashimoto, Toshihiro Molecules Article Yellow pigments, fomitellanols A (1a) and B (2a), and drimane-type sesquiterpenoid ethers of isocitric acid, cryptoporic acids P (3) and Q (4), have been isolated fromthe fruiting bodies of Fomitellafraxinea (Polyporaceae). Their structures were established by a combination of extensive NMR spectroscopy and/or X-ray crystallographic analyses, and their biological activity against COX-1, COX-2, and 5-LO was investigated. MDPI 2013-04-09 /pmc/articles/PMC6270288/ /pubmed/23571531 http://dx.doi.org/10.3390/molecules18044181 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yoshikawa, Kazuko
Koso, Kazuaki
Shimomura, Masumi
Tanaka, Masami
Yamamoto, Hirofumi
Imagawa, Hiroshi
Arihara, Shigenobu
Hashimoto, Toshihiro
Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO
title Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO
title_full Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO
title_fullStr Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO
title_full_unstemmed Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO
title_short Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO
title_sort yellow pigments, fomitellanols a and b, and drimane sesquiterpenoids, cryptoporic acids p and q, from fomitella fraxinea and their inhibitory activity against cox and 5-lo
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270288/
https://www.ncbi.nlm.nih.gov/pubmed/23571531
http://dx.doi.org/10.3390/molecules18044181
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