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Sodium Valproate Induces Cell Senescence in Human Hepatocarcinoma Cells

Hepatocarcinogenesis is associated with epigenetic changes, including histone deacetylases (HDACs). Epigenetic modulation by HDAC inhibition is a potentially valuable approach for hepatocellular carcinoma treatment. In present study, we evaluated the anticancer effects of sodium valproate (SVP), a k...

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Detalles Bibliográficos
Autores principales: An, Hong-Mei, Xue, Yong-Fei, Shen, Yan-Li, Du, Qin, Hu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270308/
https://www.ncbi.nlm.nih.gov/pubmed/24304587
http://dx.doi.org/10.3390/molecules181214935