Cargando…
Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests
Fraxinellone, a well-known and significant naturally occurring compound isolated from Meliaceae and Rutaceae spp. has been widely used as a drug for the treatment of tumors. On the other hand, fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibitio...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270312/ https://www.ncbi.nlm.nih.gov/pubmed/23455666 http://dx.doi.org/10.3390/molecules18032754 |
_version_ | 1783376670457069568 |
---|---|
author | Lü, Min Wu, Wenjun Liu, Huixia |
author_facet | Lü, Min Wu, Wenjun Liu, Huixia |
author_sort | Lü, Min |
collection | PubMed |
description | Fraxinellone, a well-known and significant naturally occurring compound isolated from Meliaceae and Rutaceae spp. has been widely used as a drug for the treatment of tumors. On the other hand, fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. The present study focused on the antifeedant and larvicidal activities of fraxinellone against the larvae of Lepidoptera, including Mythimna separata, Agrotis ypsilon, Plutella xylostella, and one kind of sanitary pest, Culux pipiens pallens. Meanwhile, the ovicidal activities and the effects of fraxinellone on the larval development of M. separata were also observed. The LC(50) values of fraxinellone against 3rd instar larvae of M. separata, 2nd instar larvae of P. xylostella and 4th instar larvae of C. pipiens pallens were 15.95/6.43/3.60 × 10(−2) mg mL(−1), and its AFC(50) values against 5th instar larvae of M. separata, 2nd instar larvae of P. xylostella and 2nd instar larvae of A. ypsilon were 10.73/7.93/12.58 mg mL(−1), respectively. Compared with the control group, fraxinellone obviously inhibited the pupation rate and the growth of M. separata. Once M. separata was treated with fraxinellone at concentrations of 5.0, 10.0, and 20.0 mg mL(−1), respectively, the stages from the larvae to adulthood and the egg hatching duration were prolonged to 1/2/3, and 4/3/4 days, respectively. Additionally, fraxinellone strongly inhibited the development rate and the egg hatch proportion of M. separata. |
format | Online Article Text |
id | pubmed-6270312 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62703122018-12-20 Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests Lü, Min Wu, Wenjun Liu, Huixia Molecules Article Fraxinellone, a well-known and significant naturally occurring compound isolated from Meliaceae and Rutaceae spp. has been widely used as a drug for the treatment of tumors. On the other hand, fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. The present study focused on the antifeedant and larvicidal activities of fraxinellone against the larvae of Lepidoptera, including Mythimna separata, Agrotis ypsilon, Plutella xylostella, and one kind of sanitary pest, Culux pipiens pallens. Meanwhile, the ovicidal activities and the effects of fraxinellone on the larval development of M. separata were also observed. The LC(50) values of fraxinellone against 3rd instar larvae of M. separata, 2nd instar larvae of P. xylostella and 4th instar larvae of C. pipiens pallens were 15.95/6.43/3.60 × 10(−2) mg mL(−1), and its AFC(50) values against 5th instar larvae of M. separata, 2nd instar larvae of P. xylostella and 2nd instar larvae of A. ypsilon were 10.73/7.93/12.58 mg mL(−1), respectively. Compared with the control group, fraxinellone obviously inhibited the pupation rate and the growth of M. separata. Once M. separata was treated with fraxinellone at concentrations of 5.0, 10.0, and 20.0 mg mL(−1), respectively, the stages from the larvae to adulthood and the egg hatching duration were prolonged to 1/2/3, and 4/3/4 days, respectively. Additionally, fraxinellone strongly inhibited the development rate and the egg hatch proportion of M. separata. MDPI 2013-03-01 /pmc/articles/PMC6270312/ /pubmed/23455666 http://dx.doi.org/10.3390/molecules18032754 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Lü, Min Wu, Wenjun Liu, Huixia Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests |
title | Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests |
title_full | Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests |
title_fullStr | Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests |
title_full_unstemmed | Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests |
title_short | Insecticidal and Feeding Deterrent Effects of Fraxinellone from Dictamnus dasycarpus against Four Major Pests |
title_sort | insecticidal and feeding deterrent effects of fraxinellone from dictamnus dasycarpus against four major pests |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270312/ https://www.ncbi.nlm.nih.gov/pubmed/23455666 http://dx.doi.org/10.3390/molecules18032754 |
work_keys_str_mv | AT lumin insecticidalandfeedingdeterrenteffectsoffraxinellonefromdictamnusdasycarpusagainstfourmajorpests AT wuwenjun insecticidalandfeedingdeterrenteffectsoffraxinellonefromdictamnusdasycarpusagainstfourmajorpests AT liuhuixia insecticidalandfeedingdeterrenteffectsoffraxinellonefromdictamnusdasycarpusagainstfourmajorpests |